Author/Editor		Skok, Pavel
Title		Neobičajen zaplet pri Crohnovi bolezni - predstavitev bolnice
Translated title		Unusual complication in Crohn's disease - case presentation
Type		članek
Source		In: Gričar M, Vajd R, editors. Urgentna medicina: izbrana poglavja 2010. Zbornik 17. mednarodni simpozij o urgentni medicini; 2010 jun 9-12; Portorož. Ljubljana: Slovensko združenje za urgentno medicino,
Publication year		2010
Volume		str. 192-4
Language		slo
Abstract		Introduction. The course of Crohn's disease is frequently characterized by extraintestinal manifestations. Case presentation. A 22-year patient was transferred to our institution due to fever (40⁰C), diarrhea and disseminated erythematous plaques on the arms, legs, trunk and face. Six month previously Crohn's disease of the small intestine, ileum and sigmoid colon was diagnosed with colonoscopy and biopsies. In the diagnostic procedure, viral and other infections were excluded and after consultation skin biopsy was performed, confirming a dense infiltration of neutrophilic polymorphonuclear leukocytes, establishing the diagnosis of Sweet's syndrome. Treatment with high doses of methylprednisolone resulted in a rapid improvement. Conclusion. Acute febrile neutrophilic dermatosis, Sweet's syndrome, is considered one of the extraintestinal manifestations of Crohn's disease. Early diagnosis of this syndrome is important because of the prompt response to treatment with corticosteroids.
Summary		Uvod. Med značilnosti Crohnove bolezni sodijo tudi različna zunajčrevesna bolezenska znamenja. Predstavitev bolnice. 22-letno bolnico smo sprejeli na oddelek zaradi povešane telesne temperature (do 40⁰C), drisk in razširjenih eritematoznih sprememb na koži, ki so se pojavili na okončinah, prsnem košu in obrazu. Šest mesecev pred sprejemom so pri bolnici endoskopsko in patohistološko ugotovili Crohnovo bolezen tankega črevesa, ileuma in sigmoidnega dela debelega črevesa, zato je bilo uvedeno zdravljenje z mesalazinom in budezonidom. V diagnostičnem postopku smo pri bolnici izključili različne virusne in druge okužbe. S patohistološko analizo kožnih sprememb smo potrdili akutno febrilno neutrofilno dermatozo in uvedli zdravljenje z visokimi odmerki metilprednizolona, ki je bilo uspešno. Zaključek. Akutna febrilna neutrofilna dermatoza, imenovana tudi Sweet-ov sindrom, je redek zunajčrevesni zaplet Crohnove bolezni. Hitra prepoznava tega sindroma je ključna za uspešno zdravljenje s kortikosteroidi.
Descriptors		CROHN DISEASE