Author/Editor     Frangež, Igor
Title     Amputacija spodnje okončine: primerjava bolnikov s sladkorno boleznijo z bolniki brez sladkorne bolezni
Type     monografija
Place     Ljubljana
Publisher     Univerza v Ljubljani, Medicinska fakulteta
Publication year     2009
Volume     str. 34
Language     slo
Abstract     Background: Diabetes is the cause of about 50% of all nontraumatic lower-extremity amputations worldwide. It is estimated that the lifetime risk for amputation in patients with diabetes is 10-15%, 10-30 times higher in comparison with the general population. Most amputations in diabetic patients are due to peripheral vascular disease, peripheral neuropathy, and infection, while in nondiabetic patients peripheral vascular disease is the main cause. Aim: To compare demographic data, accompanying diseases, amputation level, mortality and parameters between patients with and without diabetes. Patients and methods: We performed a retrospective analysis of medical records of nontraumatic amputations performed on Surgical clinic at University clinical centre Ljubljana in the years 1996-2002 in patients with and without diabetes. Results: Comparison of 437 amputations in 389 diabetic patients with 251 amputations in 230 nondiabetic patients showed that diabetic amputees are younger (70.9 vs. 73.3 years, p=0,017) and have more distal amputations (38.7% transmetatarzal amputations vs. 14.7%, p=0,000). In both groups, men are more concerned than women (57.3% in diabetics and 63.1% in nondiabetics). The length of hospital stay was comparable in both groups (17.7 days in diabetics vs. 15.8 days in nondiabetics, p= 0,078). None of the patients died during operative procedure but during hospital stay mortality among nondiabetics was higher (2.0% vs. 9.1%, p=0,000). Conclusions: Our results support previous findings from literature that diabetic amputees are younger, have lower level amputations and comparable risk for complications. Only inconsistency with the literature was shown in post operative rnortality, which was higher in our nondiabetic patients probably because of older age and more frequent accompanying diseases.
Descriptors     DIABETES MELLITUS
LEG
AMPUTATION
MEDICAL RECORDS
ARTERIAL OCCLUSIVE DISEASES
RETROSPECTIVE STUDIES