Author/Editor     Erdani-Kreft, Mateja; Dragin, Urška
Title     Amnijska membrana v tkivnem inženirstvu in regenerativni medicini
Translated title     Amniotic membrane in tissue engineering and regenerative medicine
Type     članek
Source     Zdrav Vestn
Vol. and No.     Letnik 79, št. 10
Publication year     2010
Volume     str. 707-15
Language     slo
Abstract     Background: Tissue engineering is becoming an increasingly important field of regenerative medicine as it develops the biological substitutes for the purpose of restoring, maintaining or improving tissue function. Since the primary function of amniotic membrane is to surround and protect an embryo, the amniotic membrane's biological and mechanical properties categorize it as an attractive biomaterial for tissue engineering. Conclusions: We describe the properties of amniotic membrane, which has low immunogenicity, anti-microbial, anti-fibrotic, anti-scarring, as well as reasonable mechanical properties and epithelialization stimulating effects. The amniotic membrane is also a source of stem cells, which like the embryonic stem cells are pluripotent, but not tumorogenic. These various properties render the amniotic membrane a suitable source of cells or matrix for tissue engineering and regenerative medicine.
Descriptors     AMNION
AMNIOTIC FLUID
STEM CELLS
BIOMEDICAL ENGINEERING
BIOLOGICAL DRESSINGS
UROTHELIUM
REGENERATION