Author/Editor		Črešnar, B; Petrič, Š
Title		Cytochrome P450 enzymes in the fungal kingdom
Type		članek
Source		Biochim Biophys Acta
Vol. and No.		Letnik 1814, št. 1
Publication year		2011
Volume		str. 29-35
Language		eng
Abstract		Cytochrome P450 monooxygenases of fungi are involved in many essential cellular processes and play diverse roles. The enzymes catalyze the conversion of hydrophobic intermediates of primary and secondary metabolic pathways, detoxify natural and environmental pollutants and allow fungi to grow under different conditions. Fungal genome sequencing projects have enabled the annotation of several thousand novel cytochromes P450, many of which constitute new families. This review presents the characteristics of fungal cytochrome P450 systems and updates information on the functions of characterized fungal P450 monooxygenases as well as outlines the currently used strategies for determining the function of the many putative P450 enzymes.
Descriptors		FUNGI CYTOCHROME P-450 ERGOSTEROL HYDROXYLATION AMINO ACID SEQUENCE GENOME, FUNGAL NADH DEHYDROGENASE NADPH DEHYDROGENASE