Author/Editor     Mikek, Kristina; Morela, Vesna; Pahor, Dušica
Title     Srednjeročni rezulati zdravljenja keratokonusa z metodo cross-linking pri 28 očeh z napredovalo obliko keratokonusa
Translated title     Mid-term results of treatment with corneal collagen cross - linking in 28 eyes with progression of keratoconus
Type     članek
Source     Zdrav Vestn
Vol. and No.     Letnik 79, št. Suppl
Publication year     2010
Volume     str. I-89-95
Language     slo
Abstract     Background: Corneal collagen cross-linking by UVA/riboflavin represents a new treatment modality for patients suffering from progressive keratoconus. Methods: In the retrospective clinical study we showed 28 eyes with progressive keratoconus where we performed corneal cross-linking treatment. Follow up time after the treatment was from 6 to 21 months. The procedure performed was cross-linking treatment with corneal deepithelization 8 mm in diameter, application of riboflavin and UVA irradiation 3mW/cm2. Before and after treatment besides a complete ophthalmologic examination with uncorrected visual acuity (UCVA) and best corrected visual acuity (BCVA) also listed examinations were performed: corneal computerized topographic examination, pentacam examination where we measured corneal thickness and intraocular pressure (IOP) evaluation. Parameters analyzed were: UCVA, BCVA, corneal thickness, average keratometry readings, spherical equivalent (SE) and amount of astigmatism. Results: In statistical analysis we proved that in the three parameters analyzed there was statistical significant difference as before treatment: uncorrected visual acuity, best corrected visual acuity and corneal thickness. In other paramethers analyzed - mean keratometry readings, spherical equivalent and amount of astigmatism there was no statistical significant difference in comparison before and after treatment. With the method of linear regression we proved that on the best corrected visual acuity after the treatment the most influence was in best corrected visual acuity before treatment and the degree of keratoconus, other parameters before treatment acuity and corneal thickness. In other paramethers analyzed - mean keratometry readings, spherical equivalent and amount of astigmatism there was no statistical significant difference in comparison before and after treatment. (Abstract truncated at 2000 characters)
Descriptors     KERATOCONUS
RIBOFLAVIN
ULTRAVIOLET THERAPY
VISUAL ACUITY
TREATMENT OUTCOME
RETROSPECTIVE STUDIES