Author/Editor		Rodi, Z
Title		Preiskava križničnega živčevja pri bolnikih z multiplo sklerozo
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1994
Volume		str. 66
Language		slo
Abstract		Neurophysiological investigations of sacral nervous system along with pudendal and tibial nerve cortical somatosensory evoked responses were performed in a group of 10 male and 16 female patients with clinically definite multiple sclerosis. Patients had mild to severe neurological disability, with a history of micturition disorders in 85 per cent. Constipation was noted in 65 per cent of questioned patients. Quantitative electromyography of the external anal sphincter was abnormal in 65 per cent and pudendo-anal reflex in 35 per cent of patients. Pudendal cortical somatosensory evoked potentials showed abnormality in 46 per cent and tibial responses in 81 per cent of patients. The tibial cortical somatosensory evoked potentials proved to be more sensitive in revealing conduction disturbance in somatosensory pathway than pudendal responses. While tibial responses were abnormal in mildly, pudendal responses were only abnormal in moderately disabled patients. However both evoked responses were in correlation with neurological disability. In contrast to our expectations gross electromyographic and reflex abnormalities of the external anal sphincter showed no correlation with a history of labours and constipation. This may simply be the consequence of small number of patients. Correlation was found between electromyographic abnormalities and the duration of disease. In our patients there was no correlation of electromyographic and reflex abnormalities with a history of micturition disorder. Some correlation was observed in the case of both pudendal and tibial cortical somatosensory evoked responses, but it may not be specific. In two female patients we found clinical and neurophysiological signs consistent with the lesion of medullary conus. Magnetic resonance imaging could provide information about morphological and functional correlations in such patients.
Descriptors		MULTIPLE SCLEROSIS EVOKED POTENTIALS, SOMATOSENSORY ELECTROMYOGRAPHY LUMBOSACRAL PLEXUS URINATION DISORDERS TIBIAL NERVE ANUS CONSTIPATION NEUROLOGIC EXAMINATION