Author/Editor		Benedičič, A; Bajc, B
Title		Perioralni dermatitis
Translated title		Dermatitis perioralis
Type		članek
Source		Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.		Letnik 19, št. Suppl 1
Publication year		2010
Volume		str. 87-90
Language		slo
Abstract		Perioral dermatitis is a distinctive clinical entity. Its etiology and pathogenesis have not yet been clarified. It may be triggered or aggravated by various external factors, including topical steroids, which are often prescribed for its treatment. It is manifested as a persistent erythematous eruption composed of tiny papules and papulopustules primarily distributed around the mouth. Perioral dermatitis responds promptly to tetracycline-type antibiotics. Systemic erythromicin in an alternative for patients that can not be treated with tetracycline. Isotretinoin is used for treating the granulomatous form. Topical treatment with metronidazole or erythromycin helps, but local corticosteroids are contraindicated. Relapses ara rare if the use of corticosteroids is completely stopped and use of cosmetics is limited. Untreated perioral dermatitis runs a fluctuating course. Due to its visibility and possible intense subjective symptoms, the disease impairs the quality of the patients life. However, it never threatens the patient`s life so there is no need for urgent referral. If needed, regular referral to a dermatology outpatient clinic is usual. Only in the case of severe impairment and questionable diagnosis is accelerated refferal within four weeks possible.
Summary		Perioralni dermatitis je prepoznavna bolezen kože obraza. Etiologija in patogeneza še nista dobro pojasnjeni. Sprožijo ali poslabšajo ga lahko različni zunanji dejavniki, tudi lokalni kortikosteroidi, ki jih pri tej bolezni pogosto predpisujejo. Bolezen označujejo vnetne spremembe z drobnimi papulami in papulopustulami v okolici ust. Perioralni dermatitis zdravimo s tetraciklinskimi antibiotiki. Sistemski eritromicin uporabimo, kadar so tetraciklini kontraindicirani. Granulomatozna oblika se neredko umiri šele ob uporabi izotretinoina. Lokalno zdravljenje z metronidazolom ali eritromicinom pomaga pri izboljšanju. Kortikosteroidni preparati so kontraindicirani. Ponovitve perioralnega dermatitisa so po popolni ukinitvi kortikosteroidov in ob omejeni rabi kozmetičnih izdelkov redke. Brez zdravljenja bolezen poteka s prehodnimi izboljšanji. Zaradi izraženih sprememb na vidnih mestih in lahko zelo motečih simptomov bolezen poslabša kakovost življenja bolnika, nikoli pa ne ogroža življenja, zato ni potrebe za nujno napotitev v dermatološko ambulanto. Običajna je redna napotitev, le ob močno izraženi bolezni ali ob dvomu v pravilnost diagnoze je možna hitra napotitev za pregled v štirih tednih.