Author/Editor     Bruckbauer, HR; Hofmann, H
Title     Skin manifestations in Lyme borreliosis
Type     članek
Source     Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.     Letnik 3, št. 1-2
Publication year     1994
Volume     str. 37-48
Language     eng
Abstract     The dermatological manifestations of Lyme borreliosis, erythema (chronicum) migrans, lymphadenosis benigna cutis and acrodermatitis chronica atrophicans, have been well known tick borne skin diseases in Europe since more than 100 years. Association with neurological symptoms and arthritis has been described. After detection of the causative agent, Borrelia burgdorferi, by Willy Burgdorfer in 1981 these diseases were seen in a new context. Thereafter new diagnostic methods and therapeutic regimes were developed. It was possible to integrate atypical clinical manifestations into the new entity. The knowledge about the different clinical forms, the ultrastructure of the microorganism, and the epidemiology increased rapidly. In the course of the infection, skin symptoms appear usually at first. As serodiagnostic methods are not very reliable in the early stages, it is necessary to know about the skin manifestations of Lyme borreliosis in order to establish the correct diagnosis as early as possible, and to avoid serious systemic disease by early treatment.
Descriptors     LYME DISEASE
SKIN MANIFESTATIONS
ERYTHEMA CHRONICUM MIGRANS
LYMPHADENITIS
ACRODERMATITIS