Author/Editor     Cerar, Andraž; Rakovec, Peter; Bunc, Matjaž
Title     Inappropriate sinus tachycardia treatment with ivabradine - three case reports
Translated title     Zdravljenje neustrezne sinusne tahikardije z ivrabradinom - predstavitev treh primerov
Type     članek
Source     Slov Kardiol
Vol. and No.     Letnik 8, št. 1-2
Publication year     2011
Volume     str. 49-51
Language     eng
Abstract     The inappropriate sinus tachycardia is a rare disease, characterized by heart rates 100 bpm or more during daytime and/or a mean heart rate of 90 bpm or more during holter monitoring. Mostly it is treated with a beta-blocker or verapamil and - if this therapy fails -transcatheter sinus node modulation is considered. For the last few years a new drug, a selective and specific If current blocker, ivabradine, has been available. We report the results of ivabradine therapy in three cases. In all of them ivabradine 5 mg bid successfully decreased the mean heart rate, measured by holter monitoring. Ivabradine therapy did not affect the exercise capacity in presented patients; however, in one patient, in whom combined therapy with bisoprolol was tested, the exercise test revealed a significant reduction in exercise capacity. Ivabradine seems to be an effective alternative for the inappropriate sinus tachycardia therapy.
Descriptors     TACHYCARDIA, SINUS
ELECTROCARDIOGRAPHY, AMBULATORY
EXERCISE TEST
ION CHANNELS
ADULT