Author/Editor		Petrin, J; Rozman, B; Dolenc, P; Logar, D; Božič, B; Vizjak, A; Ferluga, D; Jezeršek, P
Title		The dissociation of arterial hypertension and lupus glomerulonephritis in systemic lupus erythematosus
Type		članek
Source		Blood Press
Vol. and No.		Letnik 2, št. 2
Publication year		1993
Volume		str. 108-12
Language		eng
Abstract		In spite of several articles questioning the general opinion that arterial hypertension in patients with systemic lupus erythematosus (SLE) is only the consequence of lupus glomerulonephritis (LGN), this still remains the usual pathophysiologic explanation. The purpose of this study was to explore the correlations between hypertension and LGN and to assess the importance of hypertension control for the prognosis of patients. A retrospective analysis of 173 patients with SLE over a period of 14 years was performed. For most of the patients, data were available from regular follow-up visits over an average of 6 years. Our results show a dissociation of hypertension and LGN and an association of hypertension and renal dysfunction. Severe hypertensive renal vascular lesions correlated well with a decrease of renal function. Successful treatment of hypertension is therefore essential in order to prevent deterioration of renal function in patients with LGN.
Descriptors		HYPERTENSION LUPUS ERYTHEMATOSUS, SYSTEMIC LUPUS NEPHRITIS ADOLESCENCE ADULT ANTIBODIES, ANTICARDIOLIPIN BLOOD PRESSURE CHILD HYPERTENSION KIDNEY LUPUS ERYTHEMATOSUS, SYSTEMIC LUPUS NEPHRITIS MIDDLE AGE RETROSPECTIVE STUDIES