Author/Editor		Marolt-Gomišček, M; Tomažič, T; Čižman, M; Arnež, M; Muzlovič, I; Černe, L; Bem, B; Vodušek, D; Trinkaus, D
Title		Invazivne streptokokne okužbe
Translated title		Invasive streptococcal A infections
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 63, št. 12
Publication year		1994
Volume		str. 735-9
Language		slo
Abstract		Background. During the last ten years there reappeared rheumatogenic strains of group A streptococci, the number of patients with sever invasive infections increased. In addition a new syndrom known as the "streptococcal toxic-shock syndrom" has been reported in the year 1987. It is caused by streptococcal pyrogenic exotoxins. Patients and treatment. The most characteristic clinical and laboratory data about diagnosis necrotising fasciitis, myositis and streptococcal toxic-shock syndrom are noted. The treatment of invasive streptococcal infections is more successful with clindamicin or ceftriaxon than with penicillin. In this paper two patients as definite cases and two patient defined as probable toxic-shock syndrom are described. Conclusions. Although the invasive and toxic group A streptococcal infection are rare it is very important to recognize the infection and to start the treatment as soon as possible, because the course of infection is rapid and frequently fatal. Physicians must be aware of this infection, when the patient complains of severe pain in soft tissue, even if the skin is not yet involved. The developing toxic shock with multiple organ failure also needs prompt therapy.
Descriptors		STREPTOCOCCAL INFECTIONS STREPTOCOCCUS PYOGENES SHOCK, SEPTIC FASCIITIS MYOSITIS