Author/Editor     Bevc, Sebastjan
Title     Aldosteron, zaviralci aldosteronskih receptorjev in kronična ledvična bolezen
Translated title     Aldosterone, aldosterone receptor blockers and chronic kidney disease
Type     članek
Source     Zdrav Vestn
Vol. and No.     Letnik 80, št. 11
Publication year     2011
Volume     str. 838-44
Language     slo
Abstract     Chronic kidney disease (CKD) is a worldwide public health problem and an important risk factor for cardiovascular events, morbidity and mortality. The renin-angiotensin-aldosteron system (RAAS) drugs, angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers contribute to a better evaluation of patients with CKD. Despite good efficacy of mentioned drugs, progressive decline of kidney function was observed, suggesting a hypothesis that both aldosterone activity related mechanism and some RAAS independent mechanisms may result in progressive kidney failure. The author of the article described the role of aldosterone and aldosterone receptor blockers in patients with CKD.
Descriptors     KIDNEY FAILURE
ALDOSTERONE
RECEPTORS, ALDOSTERONE
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS