Author/Editor | Sharifian, M; Sari-Aslani, F; Hemmatinejad, B; Fallahzadeh, MK; Kasraee, B; Khoshandish, MJ; Miri, R; Mohammadi-Samani, S; Jowkar, F; Namazi, MR | |
Title | D-penicillamine, a potent melanogenesis inhibitor; lacks any depigmenting effect on black guinea pig skin: The first randomized, evalutor-blinded, vehicle-controlled, in vivo study | |
Type | članek | |
Source | Acta Dermatovenerol Alp Pannon Adriat | |
Vol. and No. | Letnik 20, št. 2 | |
Publication year | 2011 | |
Volume | str. 51-3 | |
Language | eng | |
Abstract | D-penicillamine is a melanogenesis inhibitor. This in vivo study on ten black guinea pigs using a 5% -penicillamine ointment showed its lack of any skin-lightening effect. The potential reasons for this ineffectiveness are discussed in the paper, which could be very helpful for researchers exploring new skin-lightening agents. | |
Descriptors | PENICILLAMINE MELANINS SKIN PIGMENTATION MONOPHENOL MONOOXYGENASE GUINEA PIGS |