Author/Editor     Sharifian, M; Sari-Aslani, F; Hemmatinejad, B; Fallahzadeh, MK; Kasraee, B; Khoshandish, MJ; Miri, R; Mohammadi-Samani, S; Jowkar, F; Namazi, MR
Title     D-penicillamine, a potent melanogenesis inhibitor; lacks any depigmenting effect on black guinea pig skin: The first randomized, evalutor-blinded, vehicle-controlled, in vivo study
Type     članek
Source     Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.     Letnik 20, št. 2
Publication year     2011
Volume     str. 51-3
Language     eng
Abstract     D-penicillamine is a melanogenesis inhibitor. This in vivo study on ten black guinea pigs using a 5% -penicillamine ointment showed its lack of any skin-lightening effect. The potential reasons for this ineffectiveness are discussed in the paper, which could be very helpful for researchers exploring new skin-lightening agents.
Descriptors     PENICILLAMINE
MELANINS
SKIN PIGMENTATION
MONOPHENOL MONOOXYGENASE
GUINEA PIGS