Author/Editor		Omejec, Gregor; Zupanc, Aleksander; Podnar, Simon
Title		Dolgoročne posledice po prebolelem Guillain-Barréjevem sindromu
Translated title		Long-term outcome after Guillain-Barré syndrome
Type		članek
Source		Rehabilitacija
Vol. and No.		Letnik 10, št. 2
Publication year		2011
Volume		str. 50-5
Language		slo
Abstract		Background: Guillain-Barré syndrome (GBS) causes fast progressive and symmetric weakening of muscles. Despite favorable long-term prognosis, GBS can cause serious neurological The aim of this study was to conduct a literature review and determine the outcome of GBS more than one year after the disease onset. Methods: Using PubMed, MEDLINE and DiKUL (Digital Library of the University of Ljubljana) databases, the literature published between 1995 and 2011 was reviewed. Key words Guillain-Barré syndrome and outcome were used. Results: Twelve papers on GBS outcome more than one year after disease onset were found. Excellent functional recovery was achieved by 69-100% of persons and general health was still improving in one third. The most frequent findings on neurologic examination were muscle weakness, fatigue, sensory disturbances and pain. Psychological and sexual dysfunctions were also frequently reported, although the latter have not been systematically studied. Adjustments had to be made at work, home and in leisure activities. In general, GBS patients had lower quality of life. In children, neurological consequences were mild and did not affect general functioning. Conclusions: Recovery after GBS is a long-term process, which may take 2-3 years. Although majority of individuals achieve independent gait, persisting physical, psychological and social consequences lower the quality of life. Rehabilitation program should therefore be long-term and holistic.
Summary		Izhodišča: Guillain-Barréjev sindrom (GBS) povzroča hitro napredujoče in simetrično zmanjšanje mišične moči, kljub ugodni dolgoročni prognozi pa imajo lahko osebe po prebolelem GBS tudi težje okvare živčevja. Namen prispevka je bil pregledati literaturo ter določiti dolgotrajne posledice po prebolelem GBS najmanj leto dni po njegovem izbruhu. Metode: Literaturo smo iskali v elektronskih podatkovnih zbirkah: PubMed, MEDLINE in DiKUL (Digitalna Knjižnica Univerze v Ljubljani) za obdobje od leta 1995 do leta 2011. Uporabili smo ključni besedi Guillain-Barré syndrome in outcome. Rezultati: Posledice prebolelega GBS je najmanj leto dni po njegovem izbruhu preučevalo 12 študij. Odlično funkcijsko okrevanje je doseglo 69-100 % posameznikov, zdravstveno stanje pa se je pri tretjini še naprej izboljševalo. Najpogostejše ugotovitve pri kliničnem nevrološkem pregledu posameznikov so bile zmanjšana mišična moč, utrudljivost, motnje senzibilnostiin bolečina. Pogoste so bile še duševne in spolne motnje, čeprav slednjih niso velikokrat preučevali. Zaradi posledic prebolelega GBS so posamezniki morali prilagoditi svoj način življenja pri zaposlitvi, osnovnih vsakodnevnih opravilih in preživljanju prostega časa, kakovost njihovega življenja pa je bila v primerjavi z zdravimi ljudmi slabša. Pri otrocih so bile posledice okvar živčevja večinoma blage in niso vplivale na njihovo funkcioniranje. Zaključki: Okrevanje posameznikov po GBS je dolgotrajno in lahko traja tudi 2 do 3 leta. Večina oseb doseže samostojnost pri hoji, vendar pa tako telesne kot tudi duševne in socialne posledice poslabšajo kakovost njihovega življenja in terjajo nekatere prilagoditve. Program rehabilitacije naj bo zato dolgotrajen in predvsem celosten.
Descriptors		ACTIVITIES OF DAILY LIVING QUALITY OF LIFE TREATMENT OUTCOME