Author/Editor     Milisav, Irina
Title     Clinical importance of cellular responses to stress
Type     članek
Source     HeathMed
Vol. and No.     Letnik 6, št. 2
Publication year     2012
Volume     str. 407-12
Language     eng
Abstract     The organisms and their cells are exposed to many internal and external stimuli, some of which induce stresses. These trigger responses which may change cellular responses to subsequent environmental signals or even cause cell death. There are four main types of cellular responses: induction of cell repair mechanisms, temporary adaptation to some stressors, autophagy, and cell death. As the consequences of the above mentioned processes may change the responses of cells and organisms to subsequent environmental signals or even cause cell death, the cellular stress responses must be taken into account when studying the degenerative disorders, diseases associated with aging, tumorigenesis and when the cells are used for therapies and in regenerative medicine.
Descriptors     STRESS
CELL DEATH
DNA DAMAGE
DNA REPAIR
GENE EXPRESSION
TRANSCRIPTION, GENETIC
TRANSLATION, GENETIC
ADAPTATION, PHYSIOLOGICAL
AUTOPHAGOCYTOSIS
APOPTOSIS