Author/Editor | Milisav, Irina | |
Title | Clinical importance of cellular responses to stress | |
Type | članek | |
Source | HeathMed | |
Vol. and No. | Letnik 6, št. 2 | |
Publication year | 2012 | |
Volume | str. 407-12 | |
Language | eng | |
Abstract | The organisms and their cells are exposed to many internal and external stimuli, some of which induce stresses. These trigger responses which may change cellular responses to subsequent environmental signals or even cause cell death. There are four main types of cellular responses: induction of cell repair mechanisms, temporary adaptation to some stressors, autophagy, and cell death. As the consequences of the above mentioned processes may change the responses of cells and organisms to subsequent environmental signals or even cause cell death, the cellular stress responses must be taken into account when studying the degenerative disorders, diseases associated with aging, tumorigenesis and when the cells are used for therapies and in regenerative medicine. | |
Descriptors | STRESS CELL DEATH DNA DAMAGE DNA REPAIR GENE EXPRESSION TRANSCRIPTION, GENETIC TRANSLATION, GENETIC ADAPTATION, PHYSIOLOGICAL AUTOPHAGOCYTOSIS APOPTOSIS |