Author/Editor     Morais, P; Baudrier, T; Santos, A; Mota, A; Duarte, AF; Ventura, J; Azevedo, F
Title     Parallel development and course of pheochromocytoma and giant squamous cell carcinoma of the leg: a new paraneoplastic syndrome?
Type     članek
Source     Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.     Letnik 20, št. 4
Publication year     2011
Volume     str. 221-4
Language     eng
Abstract     Paraneoplastic syndromes (PS) are diseases or symptom complexes associated with malignancy, usually of internal origin, but not directly related to mass effects, invasion, or metastatic spread. Rarely, cutaneous squamous cell carcinoma (SCC) may be associated with PS. We present a patient with a giant SCC located on the right leg and a pheochromocytoma. Considering the concurrent onset and parallel course of both pheochromocytoma and SCC in this patient, and the complete resolution of the endocrine abnormalities after resection of the skin tumor, it was possible to conceive of the pheochromocytoma as a paraneoplastic phenomenon. To our knowledge, this association has not been previously described.
Descriptors     PHEOCHROMOCYTOMA
SKIN NEOPLASMS
CARCINOMA, SQUAMOUS CELL
PARANEOPLASTIC SYNDROMES
ADULT