Author/Editor     Svetina, Saša
Title     On the vesicular origin of the cell cycle
Type     članek
Source     In: Seckbach J, editor. Genesis - in the beginning: precursors of life, chemical models and early biological evolution. Dordrecht: Springer,
Publication year     2012
Volume     str. 757-73
Language     eng
Abstract     The relation between the phenomena of cell cycle and vesicle self-reproduction has been investigated. It is proposed that vesicle self-reproduction is a process whose mechanism, based on commonly accepted physicochemical principles, could be an essential factor in the transition from the nonliving to the living world. This proposal is supported by first demonstrating the vesicle properties that are relevant to this process. A prototype model of vesicle self-reproduction and its possible generalization are then described. Parallels are drawn between the behavior of the cell cycle and the process of vesicle self-reproduction. The suggestion that the cell cycle is an upgraded version of vesicle self-reproduction is substantiated by ascribing to the latter process the ability to evolve on the basis of selection between vesicle populations.
Descriptors     BIOPHYSICS
CELL CYCLE
BIOGENESIS
CELL MEMBRANE
INCLUSION BODIES