| Author/Editor | Bizjak-Schwartzbartl, M | |
| Title | Citomorfološke, citokemične in imunološke značilnosti malignih limfomov ne-Hodgkinovega tipa pri aspiracijski biopsiji bezgavk | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Medicinska fakulteta | |
| Publication year | 1992 | |
| Volume | str. 118 | |
| Language | slo | |
| Abstract | Non-Hodkin lymphomas (NHL) form a rare group of diseases of the lymphoreticulum cell system, representing approximately 2 per cent of all malignant diseases in Slovenia. This heterogenous group of lypmhomas is morphologicaly difficult to define. The problem is further complicated by the numerous classifications in use which reflect the heterogeneity of NHL. Our experience as well as the experience of other cytologists in the field of cytodiagnosis of NHL are insufficient. Cytology being usually the only preoperative microscopic diagnostic method, and considering that in up to 25 per cent of NHL patients surgery is not possible, a profound knowledge of the cytomorphology of NHL as well as the use of additional diagnostic methods (cytochemical, immunological etc.) are required in order to improve NHL diagnosis. Apart from its role in the primary diagnosis of NHL, cytology has been proven useful also for the evaluation of disease extend, selection of the lymph node most representative for histologic verification of the process, and particularly for the microscopic verification of NHL recurrence. Our study was aimed to establish cytomorphologic, cytochemical and immunologic characteristics of NHL in fine needle aspiration biopsy (FNAB) samples. Our analysis was done on 159 histologically verified NHL classified according to Kiel classification system, in order to asses the number of individual cell type present in FNAB samples of particular subgroups, and to describe their morphologic features. For the purpose of this study various cytochemical and immunological methods enablin g the diagnosis. | |
| Descriptors | LYMPHOMA, NON-HODGKIN'S IMMUNOHISTOCHEMISTRY BIOPSY, NEEDLE HISTOCYTOCHEMISTRY DIAGNOSIS, DIFFERENTIAL CELL COUNT LYMPHOCYTES |