Author/Editor		Čučnik, S; Kveder, T; Artenjak, A; Ulcova-Gallova, Z; Swadzba, J; Musial, J; Iwaniec, T; Avčin, T; Rozman, B; Božič, B
Title		Avidity of anti-beta2-glycoprotein I antibodies in patients with antiphospholipid syndrome
Type		članek
Source		Lupus
Vol. and No.		Letnik 21, št. 7
Publication year		2012
Volume		str. 764-5
Language		eng
Abstract		Antibodies against beta(2)-glycoprotein I (anti-beta(2)GPI) are one of the hallmarks of the antiphospholipid syndrome (APS). However, they are heterogenic regarding their epitope specificity, pathogenic mechanisms and their avidity. In the current study we present some outstanding issues about avidity of anti-beta(2)GPI antibodies. Our results confirmed that high avidity anti-beta(2)GPI are associated with thrombosis and APS, while in low avidity anti-beta(2)GPI group non-APS (predominantly systemic lupus erythematosus) patients prevailed.
Descriptors		ANTIBODY AFFINITY ADULT ANTIPHOSPHOLIPID SYNDROME AUTOANTIBODIES