Author/Editor     Steyer, A; Sagadin, M; Kolenc, M; Poljšak-Prijatelj, M
Title     Whole genome sequence analysis of bovine G6P[11] rotavirus strain found in a child with gastroenteritis
Type     članek
Source     Infect Genet Evol
Publication year     2012
Volume     str. 1-21
Language     eng
Abstract     During the rotavirus strain surveillance in Slovenia, G6P[11] bovine rotavirus strain was detected in a 5 months old boy with gastroenteritis. The strain was enrolled in a whole genome sequence analysis to determine its genome segment composition and genetic characteristics. Genotype composition for the whole genome was G6-P[11]-I2-R2-C2-M2-A13-N2-T6-E2-H3, reflecting similarities with bovine rotavirus strains. The bovine origin of the strain was confirmed in all genome segments, showing the highest nucleotide identity with bovine rotavirus strains and clustering of the RVA/Human-wt/SVN/SI-R56/07/2007/G6P[11] together with bovine rotavirus strains in phylogenetic analysis. This is the first bovine G6P[11] rotavirus strain with the whole genome analysis and the first report on rotavirus G6P[11] genotype detected in humans.
Descriptors     ROTAVIRUS
GENOME, VIRAL
GASTROENTERITIS
ROTAVIRUS INFECTIONS
GENOTYPE
PHYLOGENY
CHILD
CATTLE