Author/Editor		Čižman, Milan; Bajec, Tom; Tratar, Franci; Strancar, Katja; Mavsar-Najdenov, Brigita; Drofenik, Polonca; Balkovec, Cvetka; Salemović, Danilo; Ovnič, Alenka; Martinčič, Tatjana; Premuš Marušič, Alenka; Štefančič, Metka; Bogovič, Meta; Kobal, Nataša; Bernat, Nada; Sonc, Monika; Križman, Lučka; Globočnik, Janez; Kraševec, Mojca; Fijavž, Edita; Dolenšek, Melita; Faganeli, Nataša; Sikošek, Tatjana; Bačar, Cvetka; Urbančič, Loredana; Zorc, Marjeta; Podpečan, Jožica; Armuš Pižent, Aleksandra; Urbančič, Magdalena; Keček, Majda
Title		Poraba antibiotikov v slovenskih bolnišnicah v letu 2006 in 2007
Type		članek
Source		In: Beović B, Strle F, Čižman M, et al, editors. Okužbe povezane z zdravstvom: novosti. Infektološki simpozij; 2009 mar. Ljubljana: Klinika za infekcijske bolezni in vročinska stanja,
Publication year		2009
Volume		str. 27-34
Language		slo
Abstract		Antibiotics are among the most commonly prescribed drugs in hospitals, received by 14-67 % of inpatients. The aim of the article is to present the data about antibacterials consumption at national hospitals and ward levels in Slovenia in 2006 and 2007. The data for hospital care were collected using the Anatomic Therapeutic Classification (ATC / defined daily doses (DDD) classification (WHO version 2008). The results were expressed in DDD per 100/bed-days or DDD/100 admission and DDD per 1000 inhabitants per-day (DID). In 2006 and 2007 the total consumption of antibacterials for systemic use was 48.5 and 50 DDD/100 bed-days, or 377.5 and 338.1 DDD/100 admissions or 1.70 and 1.69 DID respectively. The consumption varied substantially among different types of hospitals and among hospitals and departments of similar type as well. Among departments in Slovenia the highest consumption was at surgical and medical ICU's followed by mixed ICU's medical, surgical, pediatric and gynecological departments. The point prevalence study in UMC Ljubljana in the year 2008 showed that 40 % of total antibiotic use in hospitals is prescribed for hospital associated infections. The data provide a basis interventions to improve antibiotic prescription, evaluation of the correlation between antibiotic consumption and resistance, assessment of quality indicators for antibiotic consumption and improvement in prescribing of antibiotics.
Summary		Antibiotiki so med najpogosteje predpisovanimi zdravili v bolnišnici. Prejema jih 14-67 % bolnikov. Namen prispevka je prikazati porabo protibakterijskih učinkovin v Sloveniji na ravni države, bolnišnic in posameznih oddelkov v letu 2006 in 2007. Za izračun porabe smo uporabljali anatomsko terapevtsko kemično (ATC) klasifikacijo in porabo izrazili v definiranih dnevnih dozah (DDD) na 100 bolnišnično oskrbnih dni (BOD), DDD/100 sprejetih bolnikov oziroma DDD/1000 prebivalcev na dan. Pri izračunu smo uporabljali verzijo Svetovne zdravstvene organizacije (SZO) 2008. Celotna uporaba protibakterijskih učinkovin v bolnišnicah v letu 2006 in 2007 je bila 46,5 in 50,0 DDD/100 BOD oziroma 377,5 in 338,1 DDD/100 sprejetih bolnikov ali 1,7 in 1,69 DDD/1000 prebivalcev na dan. Poraba se je močno razlikovala med vrsto bolnišnic kot tudi med bolnišnicami in oddelki iste vrste. Največja je bila v kirurških intenzivnih enotah, sledijo internistične in mešane intenzivne enote, interni, kirurški, pediatrični in ginekološki oddelki. Točkovna prevalenčna raziskava v UKC Ljubljana v letu 2008 je pokazala, da antibiotike predpisujemo kar v 41 % zaradi v bolnišnici pridobljenih okužb. Podatki so osnova za ukrepe za izboljšanje predpisovanja antibiotikov in raziskave, povezane med porabo antibiotikov in odpornostjo bakterij. Podatki omogočajo tudi oceno kakovosti predpisovanja in prispevajo k izboljšanju predpisovanja antibiotikov.
Descriptors		DRUG UTILIZATION HOSPITALS