| Author/Editor | Šantl-Letonja, Marija; Letonja, Mitja; Nikolajević-Starčević, Jovana; Petrovič, Danijel | |
| Title | Ultrasonographic and classical risk factors of carotid atherosclerosis in patients with type-2 diabetes mellitus | |
| Translated title | Ultrazvočni in klasični dejavniki tveganja karotidne ateroskleroze pri bolnikih s sladkorno boleznijo tipa 2 | |
| Type | članek | |
| Vol. and No. | Letnik 6, št. 1 | |
| Publication year | 2013 | |
| Volume | str. 33-44 | |
| ISSN | 1855-5640 - Acta medico-biotechnica : AMB | |
| Language | eng | |
| Abstract | Namen: V raziskavi smo želeli ugotoviti prevalenco biokemičnih in kliničnih dejavnikov tveganja ter razširjenost ateroskleroze karotidnih arterij pri bolnikih s sladkorno boleznijo tipa 2 (SBT2). Metode: V prospektivno presečno študijo smo vključili 289 bolnikov s SBT2 in 157 zdravih preiskovancev. Anamnestične in klinične podatke smo zajeli z enotnim vprašalnikom. Vrednosti celokupnega holesterola, LDL in HDL holesterola, trigliceridov, glukoze, fibrinogena ter visokoobčutljivega C-reaktivnega proteina (CRP) smo določili s standardnimi biokemijskimi postopki. Aterosklerozo karotidnih arterij smo ocenili z ultrazvokom in opredelili debelino intime in medije, tip plakov ter seštevek plakov.Purpose: We determined the prevalence of the clinical and biochemical risk factors as well as the extent of atherosclerosis in carotid arteries in patients with diabetes mellitus type 2(DMT2). Methods: A total of 289 subjects with DMT2 and 157 healthy subjects were enrolled in this prospective cross-sectional study. Leveles of total cholesterol, high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglycerides, fasting, blood glucose, fribrinogen, and high-sensitivity C-reactive protein (hsCRP) were measured using standard biochemical methods. Carotid atherosclerosis was assessed by ultrasonography. Intima media thickness (IMT), plaque type and plaque score were also determined. | |
| Keywords | karotidna ateroskleroza sladkorna bolezen metabolni sindrom diabetes mellitus carotid atherosclerosis markers of atherosclerosis |