Author/Editor		Perčič, Simona; Ihan, Alojz
Title		Invazivna aspergiloza pri nekonvencionalnih bolnikih
Translated title		Invasive aspergillosis in non-conventional patients
Type		članek
Vol. and No.		Letnik 52, št. 1
Publication year		2013
Volume		str. 61-69
ISSN		0353-3484 - Medicinski razgledi
Language		slv
Abstract		Infections with Aspergillus spp. are most typically associated with invasive pulmonary aspergillosis in immunocompromised patients. However, an increasing number of reports deal with unusual manifestations of invasive aspergillosis. In the lungs, this may take the form of chronic invasive pulmonary aspergillosis, bronchocentric granulomatosis or tracheobronchitis. A number of extrapulmonary infections have been noted, sometimes in immunocompetent individuals. Examples include vertebral osteomyelitis, primary cutaneous aspergillosis, prosthetic vascular graft infection, infective endocarditis, post-operative aspergillosis and aspergillosis in the intensive care unit. Invasive aspergillosis has a myriad of clinical presentations. It has been known for many years that in disseminated aspergillosis the fungus can grow in a hu ge variety of organs. However, the current clinical challenge is early detection of invasive aspergillosis isolated to unusual sites, sometimes even in immunocompetent individuals. The combination of early diagnosis, appropriate treatment with voriconazole, and careful consideration of adjunctive surgical therapy should improve the outcome of such patients.
Keywords		invasive aspergillosis unconventional patients diagnosis invazivna aspergiloza nekonvencionalna obolenja diagnoza