Author/Editor     Kelc, Robi; Trapečar, Martin; Vogrin, Matjaž; Cencič, Avrelija
Title     Skeletal muscle derived cell cultures as potent models in regenerative medicine research
Type     članek
Vol. and No.     Letnik 47, št. 4
Publication year     2013
Volume     str. 477-482
ISSN     0148-639X - Muscle & nerve
Language     eng
Abstract     Cell cultures have been used extensively by many scientists in the last decades to study various cell and tissue mechanisms. They have many advantagesover in vivo experimental models, but their limitations are to be considered as well. As skeletal muscle-derived cell cultures are becoming increasingly interesting in studies of muscle regeneration processes the question of their relevance in experiments arises according to in vivo experimental models. This article reviews studies that have simultaneously performed in vivo and in vitro experiments on skeletal muscle and discusses the correlation of both results. Although they seem to correlate, no such studies on humans have been performed so far.
Keywords     skeletal muscle cell
cell culture
In vivo
In vitro
experimental model