Author/Editor		Hodolič, Marina; Maffione, Anna Margherita; Fettich, Jurij; Gubina, Borut; Cimitan, Marino; Rubello, Domenico
Title		Metastatic Prostate Cancer Proven by 18F-FCH PET/CT Staging Scan in Patient With Normal PSA but High PSA Doubling Time
Type		članek
Vol. and No.		Letnik 38, št. 9
Publication year		2012
Volume		str. 739-740
ISSN		0363-9762 - Clinical nuclear medicine
Language		eng
Abstract		A 59-year-old man presented with frequent urination. Six months ago, his prostate-specific antigen (PSA) was 1.56 ng/mL; currently it is 3.5 ng/mL (PSA doubling time = 6 months; PSA velocity = 0.19 ng/mL/mo). Biopsy revealed aggressive prostate cancer (Gleason score 5 + 5). Staging with F-fluorocholine PET/CT (F-FCH PET/CT) demonstrated lymph node metastasis. After 6 months of hormonal therapy with goserelin, PSA decreased to 0.38 ng/mL. A F-FCH PET/CT restaging scan demonstrated a global reduction of F-FCH lesion uptake with disappearance of some mediastinal and iliac pelvic lymph node activity.
Keywords		prostate cancer PSA doubling time fluorocholine PET/CT staging