Author/Editor		Hinni, Michael L.; Strojan, Primož
Title		Surgical margins in head and neck cancer
Type		članek
Vol. and No.		Letnik 35, št. 9
Publication year		2013
Volume		str. 1362-1370
ISSN		1097-0347 - Head & neck
Language		eng
Abstract		Adequate resection margins are critical to the treatment decisions and prognosis of patients with head and neck squamous cell carcinoma (HNSCC). However, there are numerous controversies regarding reporting and interpretation of the status of resection margins. Fundamental issues relatingto the basic definition of margin adequacy, uniform reporting standards for margins, optimal method of specimen dissection, and the role of intraoperative frozen section evaluation, all require further clarification and standardization. Future horizons for margin surveillance offer the possible use of novel methods such as molecular margins and contact microscopic endoscopy, However, the limitations of these approaches need to be understood. The goal of this review was to evaluate these issues to define a more rational, standardiyed approach for achieving resection margin adequacy for patients with HNSCC undergoing curative resection.
Descriptors		Head and neck neoplasms Neoplasm invasiveness Intraoperative period Frosen sections Carcinoma, squamous cell Surgery Pathology
Keywords		rak glave rak vratu onkologija