Author/Editor		Sartelli, Massimo; Catena, Fausto; Ansaloni, Luca; Leppaniemi, Ari; Taviloglu, Korhan; Goor, Harry van; Viale, Pierluigi; Lazzareschi, Daniel Vasco; Coccolini, Federico; Corbella, Davide; Pintar, Tadeja
Title		Complicated intra-abdominal infections in Europe
Type		članek
Vol. and No.		Letnik 7, št. 36
Publication year		2012
ISSN		1749-7922 - World journal of emergency surgery : WJES
Language		eng
Abstract		The CIAO Study (Complicated Intra-Abdominal infection Observational Study) is a multicenter investigation performed in 68 medical institutions throughoutEurope over the course of a 6-month observational period (January-June 2012).Patients with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study.2,152 patients with a mean age of 53.8 years (range: 4--98 years) were enrolled in the study. 46.3% of the patients were women and 53.7% were men. Intraperitoneal specimens were collected from 62.2% of the enrolled patients, and from these samples, a variety of microorganisms were collectively identified. The overall mortality rate was 7.5% (163/2.152).According to multivariate analysis of the compiled data, several criteria were found to be independent variables predictive of patient mortality, including patient age, the presence of an intestinal non-appendicular source of infection (colonic non-diverticular perforation, complicated diverticulitis, small bowel perforation), a delayed initial intervention (a delay exceeding 24 hours), sepsis and septic shock in the immediate post-operative period, and ICU admission. Given the sweeping geographical distribution of the participating medical centers, the CIAO Studygives an accurate description of the epidemiological, clinical, microbiological, and treatment profiles of complicated intra-abdominal infections (IAIs) throughout Europe.
Keywords		abdominalna kirurgija infekcije Evropa raziskave CIAO Study