Author/Editor		Van Kaam, Anton H.; Rimensberger, Peter C.; Borensztajn, Dorine; De Jaegere, Anne P.; Štucin Gantar, Irena
Title		Ventilation practices in the Neonatal Intensive Care Unit
Type		članek
Vol. and No.		Letnik 157, št. 5
Publication year		2010
Volume		str. 767-771
ISSN		0022-3476 - The Journal of pediatrics
Language		eng
Abstract		ObjectiveTo assess current ventilation practices in newborn infants. Study designWe conducted a 2-point cross-sectional study in 173 European neonatal intensive care units, including 535 infants (mean gestational age 28 weeks and birth weight 1024 g). Patient characteristics, ventilator settings, and measurements were collected bedside from endotracheally ventilated infants. ResultsA total of 457 (85%) patients were conventionally ventilated. Time cycled pressurelimited ventilation was used in 59% of these patients, most often combined with synchronized intermittent mandatory ventilation (51%). Newer conventional ventilation modes like volume targeted and pressure support ventilation were used in, respectively, 9% and 7% of the patients. The mean tidal volume, measured in 84% of the conventionally ventilated patients, was 5.7 2.3 ml/kg. The mean positive end-expiratory pressure was 4.5 1.1 cmH2O and rarely exceeded 7 cmH2O.ConclusionsTime cycled pressurelimited ventilation is the most commonly used mode in neonatal ventilation. Tidal volumes are usually targeted between 4 to 7 mL/kg and positive end-expiratory pressure between 4 to 6 cmH2O. Newer ventilation modes are only used in a minority of patients.
Keywords		Fraction of inspired oxygen HFV High-frequency ventilation IQR Neonatal intensive care unit PIP Peak inspiratory pressure PEEP Positive end-expiratory pressure