Author/Editor		Hočevar, Alojzija; Lestan, Boris; Sodin-Šemrl, Snežna; Lakota, Katja; Kojc, Nika; Potočnik, Nataša; Tomšič, Matija
Title		AA amyloidosis in a polyarteritis nodosa patient treated with tocilizumab
Type		članek
Vol. and No.		Letnik 20, št. 4
Publication year		2013
Volume		str. 275-276
ISSN		1744-2818 - Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
Language		eng
Abstract		Amyloid A (AA) (secondary) amyloidosis represents a severe complication of chronic inflammatory diseases. Since pathogenic mechanisms point to the central role of interleukin 6 (IL-6) in the process of amyloid AA generation, IL-6 blockade seems an attractive therapeutic option. We report a case of a patient with polyarteritis nodosa complicated by AA amyloidosis treated with tocilizumab.
Keywords		polyarteritis nodosa renal failure secondary amyloidosis nodozni poliarteritis ledvična odpoved sekundarna amiloidoza