| Author/Editor | Ferant, Žan; Kozar, Nejc; Dolinšek, Jernej; Šikić Pogačar, Maja; Mičetić-Turk, Dušanka | |
| Title | Bone mineral density and body composition in pediatric patients with celiac disease and inflammatory bowel disease | |
| Type | članek | |
| Vol. and No. | Letnik 8, št. 3 | |
| Publication year | 2014 | |
| Volume | str. 319-328 | |
| ISSN | 1840-2291 - HealthMED : Journal of Society for development in new net environment in B&H | |
| Language | eng | |
| Abstract | Background: Celiac disease (CD) and inflammatory bowel disease (IBD) are frequently associated with reduced bone mineral density (BMD). In the present study we investigated bone mineral density in pediatric patients with either CD or IBD in stable remission and compared them with their peers. Furthermore, we investigated the applicability of bioimpedance analysis (BIA) as a diagnostic tool for lowered BMD. Methods: Altogether, 104 children aged between 10 and 18 years (49 boys, 55 girls) were selected and followed-up. Lumbar and left hip BMD were measured using dual-energy X-ray absorptiometry (DXA), and results expressed as Z scores for a specific chronological age. CD and IBD were diagnosed previously in each test group and children/adolescents were treated accordingly. Additionally, levels of vitamin D were determined in all the groups including control. Percentage of body fat (BF %) and lean body mass (LBM) were measured using BIA method. Results: BMD did not differ significantly between CD, IBD or control group. In CD and IBD group vitamin D levels were significantly lower than in the control group (p < 0.01). Conclusion: Results of the present study showed that pediatric patients with CD and IBD in a stable remission have good BMD. As vitamin D levels in both test groups were significantly lower than in the control, supplementation of vitamin D should be considered in order to prevent possible long term deteriorations of bone mineral mass. Our results showed that BIA is not a reliable method in determining lowered BMD. | |
| Keywords | mineralna kostna gostota celiakija kronična vnetna črevesna bolezen vitamin D telesna maščoba otrok mladostnik pediatrija |