Author/Editor     Gregorič, Igor; Radovancevic, Rajko; Patel, Manish; Fenik, Yelena; Cohn, William E.; Frazier, O.H.
Title     Use of sealed grafts In The Heartmate II Left Ventricular Assist Device Inflow and outflow conduits
Type     članek
Publication year     2014
ISSN     1058-2916 - ASAIO journal (American Society for Artificial Internal Organs : 1992)
Language     eng
Abstract     Gelatin impregnated non-porous sealed grafts were introduced in the inflow and outflow conduits for use with the HeartMate II (HMII) to eliminate pre-clotting procedures and to reduce operative bleeding. We compared results of 67 patients who received first time LVADs with sealed inflow and outflow grafts (S-graft group) to a preceding 65 patients who received an LVAD with non-sealed grafts (NS-graft group).Overall, the amount of blood product transfusions was less in the S-graft group than in the NS-graft group (red blood cells, 4.9 % 4.5 vs. 8.0 % 9.4 units, P=0.022; fresh frozen plasma, 5.0 % 3.0 vs. 8.7 % 9.3 units, P=0.004; platelets, 2.9 % 1.1 vs. 4.5 % 3.5 units, P=0.001; and cryoprecipitate, 1.2 % 0.9 vs. 2.01 % 1.9 units, P=0.002). Within a follow-up period of 6 months, no device-related infections or strokes occurred in the S-group, but the NS-group had 1 (1.5%) driveline infections and 4 (6%) strokes. The 30-day survival rate was not significantly different between groups (P=0.053), but favored the S-group (97%) over the NS-group (88%). Use of a HMII with a sealed graft on the inflow and outflow conduits is associated with less postoperative bleeding, and may have helped to decrease the frequency of postoperative adverse events.
Keywords     left ventricular
conduits
LVAD
levi prekat
kanali
LVAD