Author/Editor     Ješe, Rok; Perdan-Pirkmajer, Katja; Dolenc-Voljč, Mateja; Tomšič, Matija
Title     A case of inverse psoriasis successfully treated with adalimumab
Type     članek
Vol. and No.     Letnik 23, št. 1
Publication year     2014
Volume     str. 21-23
ISSN     1318-4458 - Acta dermatovenerologica Alpina, Panonica, et Adriatica
Language     eng
Abstract     Inverse psoriasis is a rare form of psoriasis characterized by the involvement of skin fold areas rather than the more common psoriatic involvement of the extensor surfaces of the extremities, trunk, and scalp. In addition, it requires a modified therapeutic approach because it is often less responsive to standard treatment regimens. Current treatment recommendations for inverse psoriasis mainly consist of topical agents, including corticosteroids, calcipotriol, and immunomodulating agents, whereas systemic medications remain insufficiently studied. Although adalimumab, a TNF-% inhibitor, has been approved for the treatment of moderate to severe plaque psoriasis, some reports indicate that TNF-% inhibitors may sometimes trigger psoriatic lesions, including inverse psoriasis. However, we present a case of inverse psoriasis and psoriatic arthritis unresponsive to standard treatment that was successfully treated with adalimumab.
Keywords     inverse psoriasis
treatment
adalimumab
inverzna luskavica
zdravljenje
adalimumab