Author/Editor		Brvar, Miran
Title		Klinično pomembne razlike, prepoznava in ukrepi pri predoziranju benzodiazepinov
Translated title		Clinical features, diagnosis and treatment of benzodiapine overdose
Type		članek
Vol. and No.		Letnik 65, št. 1
Publication year		2014
Volume		str. 18-23
ISSN		0014-8229 - Farmacevtski vestnik
Language		slv
Abstract		Benzodiazepines are the most common group of drugs used in deliberate self-poisoning in Slovenia. The most frequently benzodiazepine poisoning include alprazolam, diazepam, bromazepam, lorazepam and flurazepam. Patients with a mild benzodiazepine overdose display drowsiness, dysarthria and ataxia. In large doses, benzodiazepine can cause coma and respiratory depression, and death. Flumazenil, which is a competitive antagonist of GABA receptors, can help to confirm a suspected diagnosis of benzodiazepine overdose in unconsciousness poisoned patients. The management of acute benzodiazepine poisoning is mainly supportive. In addition, flumazenil and activated charcoal could be used.
Keywords		benzodiazepini zastrupitve predoziranja benzodiazepine poisoning overdose