Author/Editor		Božič, Bojan; Guven, Jemal; Vázquez-Montejo, Pablo; Svetina, Saša
Title		Direct and remote constriction of membrane necks
Type		članek
Vol. and No.		Letnik 89, št. 5
Publication year		2014
Volume		str. 052701-1-030501-7
ISSN		1539-3755 - Physical review. E, Statistical, nonlinear, and soft matter physics
Language		eng
Abstract		The physical properties of membrane necks are relevant in vesiculation, a process that plays an essential role in cellular physiology. Because the neck's radius is, in general, finite, membrane scission and the consequent pinching off of the vesicle can only occur if it is narrowed to permit the necessary membrane topological reformation. Here we examine, in a simple single phase lipid vesicle, how external forces can promote neck constriction not only by direct compression at the neck but also, counterintuitively, by dilation at remote locations. These results provide a new perspective on the role played by actin polymerization in the process of endocytosis.
Keywords		membrane neck physical properties cellular physiology membranski vrat fizikalne lastnosti celična fiziologija