Author/Editor | Batista, U; Jezernik, K | |
Title | Morphological changes of V-79 cells after equinatoxin II treatment | |
Type | članek | |
Source | Cell Biol Int Rep | |
Vol. and No. | Letnik 16, št. 2 | |
Publication year | 1992 | |
Volume | str. 115-23 | |
Language | eng | |
Abstract | Morphological observations on the V-79-379 A cells after treatment with equinatoxin II (EqT II), isolated from the sea anemone Actina equina L., and fetal calf serum (FCS) treated toxin were examined by transmission electron microscopy. Our results showed that the cells incubated with FCS treated EqT II were almost ultrastructurally unaltered. When the cells were treated with low concentrations of EqT II alone cell ultrastructure was altered with the evidence of numerous blebs and decreased microvilli number on the cell surface and appearance of numerous vesicles in the Golgi regions. High concentrations of EqT II caused disintegration of plasmalemma and intracellular membranes as well as degradation of cytosol. | |
Descriptors | CELL MEMBRANE CNIDARIAN VENOMS CYTOPLASM ORGANELLES BLOOD CELL LINE CELL NUCLEUS CULTURE MEDIA GOLGI APPARATUS HAMSTERS INTRACELLULAR MEMBRANES MICROSCOPY, ELECTRON MICROVILLI MITOCHONDRIA |