Author/Editor		Yang, LY; Weil, MH; Noč, M; Tang, W; Turner, T; Gazmuri, RJ
Title		Spontaneous gasping increases the ability to resuscitate during experimental cardiopulmonary resuscitation
Type		članek
Source		Crit Care Med
Vol. and No.		Letnik 22, št. 5
Publication year		1994
Volume		str. 879-83
Language		eng
Abstract		OBJECTIVE: To evaluate the effect of spontaneous gasping on cardiorespiratory functions and the ability to resuscitate during experimental cardiac arrest. DATA SOURCES: Studies in rat and pig models during cardiac arrest and cardiopulmonary resuscitation (CPR). STUDY SELECTION: We retrospectively examined the role of spontaneous gasping during the course of experimental studies on cardiopulmonary resuscitation. DATA EXTRACTION: The data were extracted to illustrate the mechanisms of spontaneous gasping and its effects on pulmonary gas exchange and blood circulation during CPR. DATA SYNTHESIS: Spontaneous gasping increased PaO2 and decreased PaCO2 values during precordial compression in the absence of mechanical ventilation. The frequency of gasping during precordial compression was greater in successfully resuscitated animals. A significant linear correlation was established between coronary artery perfusion pressure and both the frequency (r2 = .90, p less th. .01) and the duration (r2 = 0.69, p less th. .01) of gasping during untreated ventricular fibrillation and before resuscitation was attempted. Like coronary perfusion pressure, the frequency and duration of gasping predicted the success of cardiac resuscitation attempts. CONCLUSIONS: Spontaneous gasping is associated with both pulmonary and hemodynamic effects during cardiac arrest in experimental animals. Spontaneous gasping is biologically useful and is predictive of a more favorable outcome of resuscitative efforts.
Descriptors		HEART ARREST RESPIRATION BLOOD CIRCULATION BLOOD GAS ANALYSIS BLOOD PRESSURE BRAIN STEM CARBON DIOXIDE DISEASE MODELS, ANIMAL HEART ARREST LINEAR MODELS OXYGEN PROGNOSIS PULMONARY GAS EXCHANGE RATS RATS, SPRAGUE-DAWLEY RESPIRATION, ARTIFICIAL RETROSPECTIVE STUDIES SWINE TIDAL VOLUME TREATMENT OUTCOME