Author/Editor		Marschalko, M; Papp, I; Biro, J; Jakob, E; Cserhalmi, JP; Horvath, A
Title		Cyclosporin for the treatment of dermatomyositis
Type		članek
Source		Acta Dermatovenerol Alp Panon Adriat
Vol. and No.		Letnik 2, št. 3
Publication year		1993
Volume		str. 87-90
Language		eng
Abstract		2 patients with extreme severe dermatomyositis, 2 patients who were at risk because of corticosteroid side effects due to underlying diseases-and 1 patient with amyopathic dermatomyosistis who resistant to previous corticosteroid treatment were treated with 5mg/kg/d cyclosporin A (CSP) and prednisone. CSP treatment has been shown to be beneficial in all 5 patients. CSP treatment was discontinued after 3 and 4 months in 2 of the patients with severe disease course because of renal side effects, which were veresible. In no cases were found underlying malignancies. CSP treatment seems to be a valuable second line drug in extreme severe cases of dermatomyositis, in cases who are at risk because of corticosteroid side effects, and in patients who are unresponsive to corticosteroid treatment.
Descriptors		CYCLOSPORINS DERMATOMYOSITIS ADRENAL CORTEX HORMONES KIDNEY DISEASES