Author/Editor		Črne, Valentina; Skvarč, Miha
Title		Diagnostični pristop pri bolniku s sumom na okužbo s Pneumocystis jirovecii
Translated title		Diagnostic approach in patients with suspected Pneumocystis jirovecii infection
Type		članek
Vol. and No.		Letnik 53, št. 3
Publication year		2014
Volume		str. 347-351
ISSN		0353-3484 - Medicinski razgledi
Language		slv
Abstract		Pneumocystis jirovecii pneumonia is common in immunocompromised patients. It has sig- nificant mortality, which is why it is important to consider an infection with P.jirovecii in these patients and use appropriate diagnostic methods. When the clinical features indi- cate P.jirovecii pneumonia. we perform imaging studies (chest radiograph and chest com- puter tomography), take blood for biochemical analysis (lactate dehydrogenase and beta-D-glucan) and respiratory speci men s for direct microscopic examination (conven- tional staining and direct immunofluorescence) or polymerase chain reaction. The best specimen is the bronchoalveolar lavage and the most sensitive and specific method is polymerase chain reaction, with which we can even detect colonization with P.jirovecii. The best way to differentiate colonization from a symptomatic infection is by taking into consideration several methods described above.
Keywords		Pneumocystis jirovecii lactate dehydrogenase beta-D-glucan Pneumocystis jirovecii laktatna dehidrogenaza beta-D-glukan