Author/Editor		Antolič, G; Šega, S; Kiauta, T
Title		Spectral analysis of heart rate variability in treated and untreated patients with essential hypertension
Type		članek
Source		In: Computers in cardiology, Chicago 1990: proceedings. Washington: IEEE Computer society,
Publication year		1990
Volume		str. 637-40
Language		eng
Abstract		By using the method of spectral analysis of heart rate variability, the function of autonomic nervous system was assessed in three groups of patients with essential hypertension: a group of newly discovered, as yet untreated patients, a group of patients chronicaly treated with atenolol (a beta-blocker) only and a group of patients under chronic treatment with nifedipine (a calcium antagonist) only. Results were compared to those obtained with a group of healthy control subjects of comparable age. While no significant differences were found between control subjects and untreated patients, a depression of indices of sympathetic activity in atenolol treated patients corroborates the hypothesis that a central mechanism of action contributes to the hypotensive action of atenolol. On the other hand, chronic treatment with nifedipine did not appreciably modify the sympatho-vagal balance.
Descriptors		HEART RATE AUTONOMIC NERVOUS SYSTEM SPECTRUM ANALYSIS ELECTROCARDIOGRAPHY NIFEDIPINE ATENOLOL HYPERTENSION SIGNAL PROCESSING, COMPUTER-ASSISTED