Author/Editor     Avšič-Županc, T; Likar, M; Novakovič, S; Čižman, B; Kraigher, A; van der Groen, G; Stojanovič, R; Obradovič, M
Title     Evidence of the presence of two hantaviruses in Slovenia, Yugoslavia
Type     članek
Source     Arch Virol Suppl
Vol. and No.     , št. Suppl 1
Publication year     1990
Volume     str. 87-94
Language     eng
Abstract     Thirty-three cases of hemorrhagic fever with renal syndrome (HFRS) have been serologically confirmed in Slovenia during the last five years. The clinical picture varied from mild to severe, with a mortality rate of 3 percent. Serum samples from 240 patients suspected of having HFRS were tested by immunofluorescence using four different hantaviral antigens. Three reactivity patterns were observed. Using capture enzyme immunoassay, IgM was detected in 100 percent acute-phase samples of patients. The distribution of hantaviral infections in small mammals was examined in two natural loci of HFRS. Two hantaviruses were found in these mammals. In one area, Clethrionomys glareolus was the predominant species, and most of their sera reacted to highes titer with Puumala virus; mild illnes was diagnosted in this area. In the second location, Apodemus flavicollis predominated, and most of the sera reacted to highest titer with Hantaan virus; severe illness was diagnosed in this area.
Descriptors     HANTAVIRUS
ANTIGENS, VIRAL
ANTIBODIES, VIRAL
MAMMALS
LUNG
SLOVENIA
HANTAVIRUS INFECTIONS
SEROTYPING