| Author/Editor | Boldyrev, AA; Kurella, EG; Rubtsov, AM; Tyulina, OV; Schara, M; Šentjurc, M | |
| Title | Direct measurement of the interactions of carnosine and its analogs with free radicals | |
| Type | članek | |
| Source | Biochemistry | |
| Vol. and No. | Letnik 57, št. 9 | |
| Publication year | 1992 | |
| Volume | str. 940-4 | |
| Language | eng | |
| Abstract | Electron spin resonance (ESR) was used to study the interaction of carnosine andits derivatives with free radicals. In a model system, production of OH radical adduct of a spin trap is found to decrease significantly in the presence of carnosine. The effect has a pronounced concentration dependence. Comparisons were made with the effects of other histidine-containing dipeptides; anserine, homocarnosine and acetylcarnosine were found to have analogous effects. Key words: ESR spectroscopy, spin trap, free radicals, histidin-containing dipeptides. | |
| Descriptors | CARNOSINE DRUG INTERACTIONS FREE RADICALS CARNOSINE ELECTRON SPIN RESONANCE SPECTROSCOPY MODELS, THEORETICAL |