Author/Editor		Lanišnik-Rižner, Tea
Title		Diagnostic potential of peritoneal fluid biomarkers of endometriosis
Type		članek
Publication year		2015
ISSN		1473-7159 - Expert review of molecular diagnostics
Language		eng
Abstract		Endometriosis is defined as the presence of endometrial glands and stroma outside the uterus, in different parts of the peritoneal cavity. It affects up to 10% of reproductive-age 10 women and up to 50% of women with infertility. Surgical diagnosis of endometriosis is still the gold standard, with no diagnostic biomarkers available. Medical therapies target the symptoms and not the disease itself, and surgical treatment cannot prevent recurrence. As peritoneal fluid reflects the altered peritoneal microenvironment of endometriosis patients, it can provide a wealth of information on pathophysiological processes and potential 15 biomarkers. This report reviews the molecular biomarkers identified in peritoneal fluid over the last 5 years and discusses their potential applications for diagnosis, prognosis and drug therapy.
Keywords		diagnosis endomitrosis systematic review diagnostika endomitroza sistematični pregled