Author/Editor     Zaletel, Marjan; Ambrožič, Aleš; Gašperšič, Nataša; Zupan, Matija; Žvan, Bojana
Title     Succecssful treatment of brain ischemia with supplementation therapy in a patient with hyperhomocystenemia
Translated title     Uspješno lječenje moždane ishemije dodacima hrani u bolesnice s hiperhomocisteinemijom
Type     članek
Vol. and No.     Letnik 50, št. 4
Publication year     2011
Volume     str. 627-631
ISSN     0353-9466 - Acta clinica Croatica
Language     eng
Abstract     The effectiveness of homocysteine-lowering therapy on stroke prevention is still unclear. Although randomized controlled epidemiological trials have yielded mixed findings, a multicenter trial did not show any beneficial effect. Genetic studies are still lacking. Therefore, we report on a female patient with transient ischemic attacks and the thermolabile variant of methylenetetrahydrofolate reductase (TT genotype), who benefited from supplemental therapy for homocysteine lowering.
Keywords     hiperhomocystenemija
ischemic attacks, transient
methylenetetrahydrofolate reductase
vitamins
dietary supplement