Author/Editor		Anderluh, Marko
Title		Pregled zdravilnih učinkovin za zdravljenje depresije
Translated title		Drugs for the treatment of depression
Type		članek
Vol. and No.		Letnik 61, št. 2
Publication year		2010
Volume		str. 66-72
ISSN		0014-8229 - Farmacevtski vestnik
Language		slv
Abstract		Depresivna motnja je najpogostejša duševna bolezen v svetovnem merilu, po predvidevanjih pa naj bi kmalu zasedla prvo mesto po pogostosti med vsemi obolenji v razvitem svetu. Potek bolezni zaznamujejo epizode depresij z vmesnimi remisijami. Zaradi kompleksne klinične slike je pogosto neprepoznana in zato nezdravljena. Farmakoterapija z antidepresivi je poleg psihoterapije glavni pristop za zdravljenje depresivnih motenj. Temelji na številnih hipotezah, ki se dopolnjujejo v zapleteno sliko etiologije bolezni. V prispevku je podana sistematična klasifikacija antidepresivov, njihov mehanizem delovanja, stranski učinki in terapevtska uporabnostDepressive disorder is the most widespread psychiatric disorder in the world and is predicted to be the leading disease of all developed world in the near future. It is frequently a chronic disease with acute phases and periods of remission. Complex clinical picture makes it hard to diagnose, and as a consequence depression often remains untreated. Pharmacotherapy with antidepressants is the major therapeutic strategy for the management of depression. It is based on numerous hypotheses, which form a complicated scheme of depression etiology. The manuscript presents classification of antidepressants, their mechanism of action, side effects and therapeutic efficiency.
Keywords		depresija antidepresivi faze zdravljenja depresije mehanizem delovanja antidepresivov