Author/Editor		Lunder, Mojca
Title		Uravnavanje telesne mase
Translated title		Regulation of body weight
Type		članek
Vol. and No.		Letnik 61, št. 2
Publication year		2010
Volume		str. 95-100
ISSN		0014-8229 - Farmacevtski vestnik
Language		slv
Abstract		Energijsko homeostazo vzdržuje več med seboj prepletenih procesov, ki jih usklajujejo možgani. Njihov cilj je vzdrževati ustrezno zalogo energije v danih pogojih okolja. V daljšem časovnem obdobju mora količina zaščite hrane zagotoviti enakovredno količino energije, kot je bila porabljena v tem obdobju. Periferne komponente regulacije vnosa hrane, kot so maščobno tkivo, pankreas, prebavni trakt, okušalni sistem in jetra, so v dvosmerni povezavi s centralnim živčevjem preko avtonomnega živčnega sistema ali hormonov in metabolitov. V centralnem živčnem sistemu poteka obdelava signalov v možganskem deblu, hipotalamusu in delih korteksa ter limbioenega sistema. Periferne informacije o prehranskem stanju organizma in informacije iz okolja se združijo in prevedejo v prilagojene vedenjske odzive - v izbire in odločitve, jesti ali ne jesti.Energy homeostasis is controlled by complex pathways, coordinated in the central nervous system with the aim to maintain energy stores at appropriate levels for given environmental conditions. Over long intervals the amount of food consumed must provide energy equivalent to the amount of energy expend. Peripheral components such as adipose tissue, pancreas, gut, gustatory system and liver are in intimate bidirectional communication with the brain through either neural connections provided by autonomic nervous system, or hormones and metabolites. In the central nervous system signals are integrated in caudal brainstem, hypothalamus and parts of cortex and limbic system. Peripheral information on nutritional status of the organism and external information are integrated and translated in behavioral responses - choices and decisions, to eat or not to eat.
Keywords		telesna masa regulacija periferni signali hipotalamus