| Author/Editor | Luštrik, Matevž; Dreu, Rok; Srčič, Stanko | |
| Title | Primerjava in razvoj naprav za oblaganje delcev | |
| Translated title | Comparison and development of particle coating | |
| Type | članek | |
| Vol. and No. | Letnik 61, št. 3 | |
| Publication year | 2010 | |
| Volume | str. 155-161 | |
| ISSN | 0014-8229 - Farmacevtski vestnik | |
| Language | slv | |
| Abstract | Tehnologija oblaganja delcev je proces, ki ga v farmacevtski industriji uporabljamo že več desetletij. Delce oblagamo z namenom prekritja neprijetnega okusa učinkovine, zaščite pred svetlobo, vlago in zračnim kisikom, iz estetskih razlogov, boljše sprejemljivosti s strani uporabnikov ter z namenom prirejanja sproščanja. V članku smo proces oblaganja delcev predstavili z vidika procesne opreme. Za oblaganje lahko uporabljamo različno opremo, ki jo širše gledano, delimo na bobne za oblaganje in vrtinčnoslojne naprave. V prvem delu so tako predstavljene nekatere najpomembnejše izboljšave na področju bobnov za oblaganje, v drugem pa sama tehnologija z vrtinčenjem skupaj z nekaterimi podvrstami naprav, ki so pripomogle k učinkovitejšemu nanašanju obloge, hkrati pa so omogočile izdelavo enakomerno obloženih delcev visoke kakovosti.Particle coating technology is a process that is being used in pharmaceutical industry for many decades. Particles are coated with the purpose of taste masking of unpalatable substances, protection from light, moisture and oxygen from the atmosphere surrounding the particles, aesthetic reasons, better acceptance by users and modified release. In this article the coating process is presented in term of process equipment. Various process equipment can be used for particle coating, which is in general divided to coating drums and fluid bed devices. The first part comprehends some of the most important improvements in drum coating technology. Additionaly the fluid bed technology is described together with certain device subtypes that have enabled more efficient coating deposition and production of high quality and uniformly coated particles. | |
| Keywords | oblaganje delcev bobni za oblaganje tehnologija z vrtinčenjem razprševanje |