Author/Editor | Gosenca, Mirjam; Gašperlin, Mirjana | |
Title | Tekoči kristali v farmaciji: struktura in metode za fizikalno-kemijsko vrednotenje | |
Translated title | Liquid crystals in pharmacy: structure and physicochemical characterization | |
Type | članek | |
Vol. and No. | Letnik 62, št. 1 | |
Publication year | 2011 | |
Volume | str. 15-25 | |
ISSN | 0014-8229 - Farmacevtski vestnik | |
Language | slv | |
Abstract | Tekoči kristali predstavljajo vmesno stanje snovi med trdnim in tekočim. Združujejo tako lastnosti tekočin (tok) kot trdnih snovi (anizotropnost, dvolomnost, urejenost). Delimo jih na termotropne in liotropne tekoče kristale glede na to, ali je za njihov nastanek potrebna povišana temperatura ali dodatek topila. V članku so opisane različne strukture termotropnih in liotropnih tekočih kristalov ter ključne metode za njihovo raziskovanje: polarizacijska in transmisijska elektronska mikroskopija, rentgensko sipanje, jedrska magnetna resonanca, mikroskopija na atomsko silo, reologija ter diferenčna dinamična kalorimetrija. Predstavljene so tudi možnosti uporabe tekočih kristalov v farmaciji in kozmetologiji.Liquid crystals are the state of matter existing between the liquid and the crystalline phase. The liquid crystalline state combines properties of both liquid and solid state and are divided in two main types, i.e. thermotropic and lyotropic liquid crystals, depending on wheather liquid crystalline state is reached either by increasing the temperature or by adding a solvent. In this article various structures of thermotropic and lyotropic liquid crystals are presented as well as relevant methods for investigation and characterization: polarized light and transmission electron microscopy, X-ray scattering, nuclear magnetic resonance, atomic force microscopy, rheology and differential scanning calorimetry. Liquid crystals for pharmaceutical application and in cosmetics are also presented. | |
Keywords | tekoči kristali struktura metode fizikalno kemijsko vrednotenje |