Author/Editor		Parpura, Vladimir; Verkhratsky, Alexei
Title		Astrogliopathology
Type		članek
Vol. and No.		Letnik 1833, št. 7
Publication year		2013
Volume		str. 1625-1631
ISSN		0167-4889 - BBA - Molecular Cell Research
Language		eng
Abstract		Pathology of the brain is caused by the de fi ciency in tissue homeostasis. As the main homeostatic element of the mammalian nervous system is represented by astrocytes, these glial cells are involved in many, if not all, brain disorders. Diseased astrocytes undergo a variety of morphological and functional changes, including deregula- tion of calcium dynamics. To rectify undesirable changes in astrocytes and/or neurones that occur in disease, we postulate the future use of nanotechnology-based therapeutics. Carbon nanotubes emerged as one of the most promising advanced nanomaterials for use in neuroprosthesis. Recently, they have been used to affect morpho-functional characteristics of astrocytes.
Keywords		astrocyte calcium carbon nanotube morphology nanotechnology nanomedicine