Author/Editor		Bonavina, L; Ancona, E; Baulieux, RA; Adham, M; Campioni, N; Pasquali, R; Orel, J; Eržen, J; Sok, M
Title		Early oesophageal cancer: results of a European multicentre survey
Type		članek
Source		Br J Surg
Vol. and No.		Letnik 82
Publication year		1995
Volume		str. 98-101
Language		eng
Abstract		Early oesophageal cancer has been extensively studied in Far-Eastern countries, where its prevalence is high. A multicentre survey was conducted within the Groupe Europen pour l'Etude des Maladies de l'Oesophage to analyse results of surgical treatment in patients with disease staged as pTis-T1 NoMo according to the tumour node metastasis classification. Of 9743 patients with squamous cell oesophageal cell oesophageal carcinoma observed since 1980, 4663 underwent resection; 253 (5.4 per cent) of these fulfilled the criteria for inclusion in the study. The overall mortality rate was 9.1 per cent (23 patients), and was higher after transthoracic than transhiatal oesophagectomy (10.7 versus 6 per cent, P not significant). Pathological examination showed an intraepithelial tumour in 46 patients (18.2 per cent), intramucosal carcinoma in 64 (23.5 per cent) and a submucosal lesion in 143 (56.5 per cent). The overall 5-year survival rate for patients with intraepithelial, intramucosal and submucosal tumours was 92.8, 72.8 and 44.3 per cent respectively. The 5-year survival rate was higher after transthoracic than transhiatal oesophagectomy (66 versus 52 per cent). No survival advantage was observed after either operation in patients with mucosal tumours. Of 21 patients with recurrent disease, 20 had a submucosal lesion. The 5-year survival rate in patients with submucosal tumour was higher after transhiatal oesophagectomy (54.2 versus 25.5 per cent).
Descriptors		ESOPHAGEAL NEOPLASMS SURVIVAL RATE EUROPE MULTICENTER STUDIES ESOPHAGECTOMY CARCINOMA, SQUAMOUS CELL PREVALENCE