Author/Editor     Rakovec, S
Title     Antimicrobial prophylaxis in emergency gastroduodenal surgery
Type     članek
Source     In: Hollender LF, de Manzini N, eds. Chirurgie d'urgence. 9e congres international de chirurgie d'urgence, Strasbourg 1989. Tome 1. Rapports et communications,
Publication year     1989
Volume     str. 158-61
Language     eng
Abstract     In the past years antimicrobial prophylaxis was used in 100 patients submitted to emergency gastroduodenal surgery at our hospital. Antibiotics were administred in a single dose about 30 minutes before the operation. 58 subjects received clindamycin, and two of them developed a postoperative infection. 42 were treated with cefotaxime, and inflammatory complications were encountered in three cases. So septic complications were observed in five of the 100 patients receiving prophylaxis (5 percent). In a control group of 75 patients without prophylaxis, undergoing surgery for the same conditions, postoperative infection occurred in fifteen cases (20 percent). The ratio between the infection rates in the group receiving prophylaxis and the control group was 1:4. If we compare the frequency of postoperative sepsis in the subgroups receiving clindamycin and cefotaxine, the ratio was 1:2. The study suggest that the frequency of infectious complications in gastroduodenal surgery can be appreciably reduced by properly indicated, choses and administraated antibiotic prophylaxis.
Descriptors     SURGICAL WOUND INFECTION
ANTIBIOTICS
GASTROINTESTINAL DISEASES